July 14, 1999 in Social Responsibility News

Levofloxacine(a Quinolone antibiotic), New Economical Process Developed

Samsung Advanced Institute of Technology(SAIT), Samsung's central R&D Center in Korea, developed the most economical method to produce Levofloxacin, which is recognized as a next-generation antibiotic with powerful antibacterial effect and safety.

The new process SAIT employed includes a unique substitution reaction which is unprecedented in Quinolone synthesis. This technology is believed to reduce the manufacturing cost of Levofloxacin to a half of the previous one due to its simplicity and mild reaction conditions.

Levofloxacine, which is an optical isomer of Ofloxacin, is known to have more powerful antibacterial effects against pneumococcus and Pseudomonas than racemate(Ofloxacin). So, it shows excellent clinical results to treat upper and lower respiratory tract infections, urinary tract infections and gynecological infectious diseases.

The world market for Levofloxacin in 1998 is estimated more than 500 million USD. SAIT has applied for five patents related to this technology and Samsung Fine Chemicals plans to produce Levofloxacin taking advantage of the new process.

Samsung Advanced Institute of Technology(SAIT) was established in October, 1987. SAIT is Samsung's main research institute committed to researching technologies aimed at the 21st century. To fulfill that commitment, SAIT is now researching many "frontier technologies" in the areas of information processing, system & control, chemistry, biomedical engineering, all of which will contribute to the well-being of the global community in the next millenium.

To learn more about the Samsung Advanced Institute of Technology, visit the website at http://www.sait.samsung.co.kr


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